environMENTAL Leveraging multi-omics data towards a molecular and neurobiological understanding of mental illness

Mental illnesses represent a huge and growing burden for Europe and globally, both at individual and societal level. A deeper molecular and neurobiological understanding of the interplay between genetic, epigenetic and environmental risk and resilience factors, including neural circuit alterations, is critical for the development of objective biomarkers and evidence-based interventions that will significantly improve mental health outcomes. I will present our strategies for fulfilling this aim using our deeply phenotyped neuroimaging clinical and population cohorts IMAGEN, STRATIFY and ESTRA.